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Serum Progranulin Levels and Disease Activity in Patients with Axial Spondyloarthritis

Irem Mercan, Pelin Oktayoglu, Nuriye Mete, Mehmet Caglayan · Aktuelle Rheumatologie · Ausgabe 03/2024 · S. 191-196

DOI 10.1055/a-2106-6930

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Autor:innenIrem Mercan, Pelin Oktayoglu, Nuriye Mete, Mehmet Caglayan
ZeitschriftAktuelle Rheumatologie
Ausgabe03/2024
Jahrgang / SeitenJg. 49 · S. 191-196

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Abstract Background Axial spondyloarthritides (ax-SpA) are a group of chronic systemic diseases of unknown aetiology, affecting mostly young men, with common features such as inflammatory low back pain, axial skeletal involvement, sacroiliitis, and association with HLA-B27. Inflammatory cytokines, mainly TNF-α, play a role in its aetiopathogenesis. Progranulin (PGRN) is thought to be an anti-inflammatory molecule th…

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Irem Mercan, Pelin Oktayoglu, Nuriye Mete, Mehmet Caglayan (2024) Serum Progranulin Levels and Disease Activity in Patients with Axial Spondyloarthritis. Aktuelle Rheumatologie, 49 (03), 191-196. https://doi.org/10.1055/a-2106-6930

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