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Frequency and new-onset rates of nausea and fatigue in ¹⁷⁷Lu-PSMA therapy with standardized premedication

Wolfram A. Bosbach, Karene Sriramachandran, Nasir Gözlügöl, Axel Rominger, Marco Cuzzocrea, Sabin G. Pop, Gaetano Paone, Irene A. Burger, Ali Afshar-Oromieh · Nuklearmedizin - NuclearMedicine · Ausgabe 05/2026 · S. 303-311

DOI 10.1055/a-2902-0532

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Autor:innenWolfram A. Bosbach, Karene Sriramachandran, Nasir Gözlügöl, Axel Rominger, Marco Cuzzocrea, Sabin G. Pop, Gaetano Paone, Irene A. Burger, Ali Afshar-Oromieh
ZeitschriftNuklearmedizin - NuclearMedicine
Ausgabe05/2026
Jahrgang / SeitenJg. 65 · S. 303-311

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Abstract-Vorschau

Abstract Aim PSMA-based radioligand therapy (PSMA-RLT) for metastatic castration-resistant prostate cancer (mCRPC) is associated with nausea, vomiting, and fatigue. We evaluated whether standardized premedication with glucocorticoids and antiemetics reduces these side effects. Methods In this retrospective multicentre study, 67 mCRPC patients received 322 cycles of 177Lu-PSMA-617 at three Swiss centres. All patients…

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Zitierempfehlung

Wolfram A. Bosbach, Karene Sriramachandran, Nasir Gözlügöl, Axel Rominger, Marco Cuzzocrea, Sabin G. Pop, Gaetano Paone, Irene A. Burger, Ali Afshar-Oromieh (2026) Frequency and new-onset rates of nausea and fatigue in ¹⁷⁷Lu-PSMA therapy with standardized premedication. Nuklearmedizin - NuclearMedicine, 65 (05), 303-311. https://doi.org/10.1055/a-2902-0532

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