CareLit · DOI-Nachweis · Aktuelle Neurologie
Multi-modal non-invasive imaging techniques show improved vector-distribution of HSV-EBV-RV hybrid vectors within experimental glioma
DOI 10.1055/s-0028-1086515
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Autor:innenA Winkeler, R.T Ullrich, Y Waerzeggers, M Sena-Esteves, H Li, B Neumaier, P Monfared, S Vollmar, J Seehafer, M Hoehn, A.H Jacobs
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
One of the main problems in gene therapy of malignant gliomas is limited vector distribution within the target tissue. To serve a more wide-spread distribution of vector-mediated gene expression throughout the tumour glioma cells can be converted to vector producer cells onsite. Conversion of tumour cells to retrovirus packaging cells has been achieved using HSV-1/EBV/RV (HER) hybrid amplicons bearing retrovirus vec…
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Zitierempfehlung
A Winkeler, R.T Ullrich, Y Waerzeggers, M Sena-Esteves, H Li, B Neumaier, P Monfared, S Vollmar, J Seehafer, M Hoehn, A.H Jacobs (2008) Multi-modal non-invasive imaging techniques show improved vector-distribution of HSV-EBV-RV hybrid vectors within experimental glioma. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086515
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