CareLit · DOI-Nachweis · Aktuelle Neurologie
PPAR gamma ablation in CD4+ T-cells augments T-cell responses in vivo and facilitates disease induction in experimental autoimmune encephalomyelitis
DOI 10.1055/s-0028-1086595
Bibliografische Angaben
Nachweis in CareLit
Autor:innenL Klotz, I Dani, B Langhans, J Alferink, T Klockgether, W Kolanus, A Waisman, P Knolle
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The peroxisome proliferator-activated receptor gamma (PPARg) belongs to a group of ligand-activated transcription factors involved in the regulation of metabolism and inflammation. PPARg is expressed in cells of the peripheral immune compartment like lymphocytes and dendritic cells, but also within the CNS, mainly in microglial cells and in neurons. Interestingly, oral administration of PPARg agonists ameliorates th…
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Zitierempfehlung
L Klotz, I Dani, B Langhans, J Alferink, T Klockgether, W Kolanus, A Waisman, P Knolle (2008) PPAR gamma ablation in CD4+ T-cells augments T-cell responses in vivo and facilitates disease induction in experimental autoimmune encephalomyelitis. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086595
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