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Altered membrane excitability following increased levels of homocysteine

C Schaub, H Beck, T Klockgether, M Linnebank · Aktuelle Neurologie · Ausgabe 09/2008

DOI 10.1055/s-0028-1086611

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Autor:innenC Schaub, H Beck, T Klockgether, M Linnebank
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Treatment with enzyme-inducting anticonvulsant drugs has been shown to be associated with increased blood levels of homocysteine. We hypothesize that elevated homocysteine levels can alter the membrane excitability of neurons, thereby altering the propensity for seizures. To address this issue, we examined primary cultures of hippocampal neurons with the whole-cell patch-clamp technique. Homocysteine was applied int…

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Zitierempfehlung

C Schaub, H Beck, T Klockgether, M Linnebank (2008) Altered membrane excitability following increased levels of homocysteine. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086611

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