CareLit · DOI-Nachweis · Aktuelle Neurologie
Paradoxical effects of a CACNA1A mutation on neurotransmitter exocytosis in hippocampal neurons
DOI 10.1055/s-0028-1086612
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Surges, F Alder, A van den Maagdenberg, D.M Kullmann, K Volynski
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Presynaptic P/Q type calcium channels mediate neurotransmitter release at synapses of the central and peripheral nervous system. Mutations in the underlying CACNA1A gene are associated with paroxysmal neurological disorders such as familial hemiplegic migraine type 1 (FHM), absence seizures and episodic ataxia. The S218L mutation results in severe FHM together with susceptibility to brain oedema. There i…
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Zitierempfehlung
R Surges, F Alder, A van den Maagdenberg, D.M Kullmann, K Volynski (2008) Paradoxical effects of a CACNA1A mutation on neurotransmitter exocytosis in hippocampal neurons. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086612
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