CareLit · DOI-Nachweis · Aktuelle Neurologie
Active immunization with amyloid-beta 1–42 induces severe memory impairment in healthy mice
DOI 10.1055/s-0028-1086620
Bibliografische Angaben
Nachweis in CareLit
Autor:innenP Vollmar, J Kullmann, B Thilo, S.R Kalluri, H.P Hartung, S Nessler, B Hemmer
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Active immunization with Amyloid-beta 1–42 (Abeta) was shown to prevent amyloid plaque deposition in different mouse models of Alzheimer's disease (AD). These effects are undoubted, whereas evidence on the improvement of memory function is still inconsistent. Here, we identify the cognitive and immunological phenotype of healthy C57BL/6 mice challenged with active Abeta immunization. Immunization significantly alter…
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Zitierempfehlung
P Vollmar, J Kullmann, B Thilo, S.R Kalluri, H.P Hartung, S Nessler, B Hemmer (2008) Active immunization with amyloid-beta 1–42 induces severe memory impairment in healthy mice. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086620
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