CareLit · DOI-Nachweis · Aktuelle Neurologie
Association of Presenilin2 genetic variations and beta-amyloid 42 level in cerebrospinal fluid of early-onset Alzheimer's disease patients
DOI 10.1055/s-0028-1086622
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC.A.F von Arnim, E Lebedeva, H Tumani, A.C Ludolph, J Kirchheiner
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Two forms of Alzheimer's disease (AD) can be distinguished: late-onset form most common in older age groups and more rarely observed early-onset form when the symptoms appear before age 65. ß-amyloid 42 (Aß42) is the major component of neuritic plaques found in brains of AD patients. Decreased Aß42 level in cerebrospinal fluid (CSF) is a biomarker for AD development. Presenilin1 (PSEN1) and presenilin2 (PSEN2) enzym…
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Zitierempfehlung
C.A.F von Arnim, E Lebedeva, H Tumani, A.C Ludolph, J Kirchheiner (2008) Association of Presenilin2 genetic variations and beta-amyloid 42 level in cerebrospinal fluid of early-onset Alzheimer's disease patients. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086622
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