CareLit · DOI-Nachweis · Aktuelle Neurologie
Analysis of neuroprotective effects of valproic acid and the analogues in motor neurons
DOI 10.1055/s-0028-1086666
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Ragancokova, F Schlesinger, K Jahn, S Petri, R Dengler, K Krampfl
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Amyotrophic lateral sclerosis (ALS) is a late-onset progressive neurodegenerative disease characterized by substantial loss of motor neurons in the spinal cord, brain stem and motor cortex. Synaptic over-excitation (excitotoxicity) of vulnerable motoneurons is thought to be of major impact for the pathophysiology of this selective neurodegeneration. Valproic acid (2-propylpentanoic acid, VPA) is one of the most freq…
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Zitierempfehlung
D Ragancokova, F Schlesinger, K Jahn, S Petri, R Dengler, K Krampfl (2008) Analysis of neuroprotective effects of valproic acid and the analogues in motor neurons. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086666
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