CareLit · DOI-Nachweis · Aktuelle Neurologie
Genome-wide screen in yeast to identify modulators of mutant SOD1 toxicity
DOI 10.1055/s-0028-1086669
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Ubmann, B Göricke, L Fichtner, I Panou, G.H Braus, M Bähr, J.H Weishaupt
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Yeast (Saccharomyces cerevisiae) cultures can be handled in a partially automated manner, and about 80% of the yeast genes have their homologous counterpart in mammalian cells. Thus, yeast mutant strains are a versatile tool for genetic studies on protein function and toxicity. In order to identify modulators and mechanisms of SOD1 toxicity, we performed a genome wide screen in Saccharomyces cerevisiae. Yeast strain…
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Zitierempfehlung
D Ubmann, B Göricke, L Fichtner, I Panou, G.H Braus, M Bähr, J.H Weishaupt (2008) Genome-wide screen in yeast to identify modulators of mutant SOD1 toxicity. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086669
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