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Temozolomide plus pegylated liposomal doxorubicine is equal to temozolomide in the first-line treatment of patients with glioblastoma – Phase I/II-study

P Hau, C Schmid, B Hirschmann, C Kleinletzenberger, M Proescholdt, G Stockhammer, A Brawanski, M Hegi, U Bogdahn · Aktuelle Neurologie · Ausgabe 09/2008

DOI 10.1055/s-0028-1086672

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Autor:innenP Hau, C Schmid, B Hirschmann, C Kleinletzenberger, M Proescholdt, G Stockhammer, A Brawanski, M Hegi, U Bogdahn
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Temozolomide (Temodar® TMZ) recently showed promising efficacy in an EORTC trial on first-line therapy of glioblastoma (GBM). Pegylated liposomal doxorubicin (Caelyx® PEG-Dox) was evaluated in patients with recurrent glioblastoma (GBM) with an overall response rate of 40%. Therefore, a combination regimen seems promising. Methods: TMZ was given orally in a dose of 75mg/m2 daily during involved field radi…

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Zitierempfehlung

P Hau, C Schmid, B Hirschmann, C Kleinletzenberger, M Proescholdt, G Stockhammer, A Brawanski, M Hegi, U Bogdahn (2008) Temozolomide plus pegylated liposomal doxorubicine is equal to temozolomide in the first-line treatment of patients with glioblastoma – Phase I/II-study. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086672

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