CareLit · DOI-Nachweis · Aktuelle Neurologie
Noradreneline deficiency aggrevates learning and memory impairment independent of Aß Levels in APPPS1 mice
DOI 10.1055/s-0028-1086716
Bibliografische Angaben
Nachweis in CareLit
Autor:innenT Hammerschmidt, M.P Kummer, A Gorji, D Terwel, D Weinshenker, H.C Pape, M.T Heneka
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Locus coeruleus (LC) degeneration and subsequent noradrenaline (NA) deficiency occur early in Alzheimers disease (AD) and may siginificantly precede amyloid-ß plaque and neurofibrillary tangle formation. The LC projects to areas that are affected in AD, including the hippocampus and enthorhinal cortex. While it is known that NA physiologically modulates long term potentiation (LTP), a cellular correlate of learning…
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Zitierempfehlung
T Hammerschmidt, M.P Kummer, A Gorji, D Terwel, D Weinshenker, H.C Pape, M.T Heneka (2008) Noradreneline deficiency aggrevates learning and memory impairment independent of Aß Levels in APPPS1 mice. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086716
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