CareLit · DOI-Nachweis · Aktuelle Neurologie
Morphological and functional changes in skeletal muscle of the Huntington's disease mouse model R6/2 suggest selective changes in fast-twitch fibres
DOI 10.1055/s-0028-1086923
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK.S Lindenberg, Z Andronache, M Orynbayev, S.L Apostol, A Riecker, C.M Kosinski, B Sellhaus, A.D Sperfeld, G.B Landwehrmeyer, W Melzer
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Skeletal muscle atrophy in Huntington's disease is usually thought to be secondary to the onset of neurological symptoms. We have studied morphological and physiological changes in skeletal muscle of the R6/2 mouse model 12–16 weeks of age. Morphological changes include an increase in centrally located nuclei and activated nuclei. In addition fibre size varies widely in the R6/2 skeletal muscle and some muscle fibre…
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Zitierempfehlung
K.S Lindenberg, Z Andronache, M Orynbayev, S.L Apostol, A Riecker, C.M Kosinski, B Sellhaus, A.D Sperfeld, G.B Landwehrmeyer, W Melzer (2008) Morphological and functional changes in skeletal muscle of the Huntington's disease mouse model R6/2 suggest selective changes in fast-twitch fibres. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086923
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