CareLit · DOI-Nachweis · Aktuelle Neurologie
iNOS gene deficiency modifies beta-amyloid deposition, cognitive performance and hippocampal long term potentiation in APPPS1 tg mice
DOI 10.1055/s-0028-1086926
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Hermes, M.P Kummer, T Hammerschmidt, D Terwel, H.C Pape, M.T Heneka
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The inducible form of the nitric oxide synthase (iNOS), is transcriptionally upregulated in response to inflammatory stimuli in Alzheimer's disease, potentially aggravating disease progression. In this study we determined the effect of iNOS deficiency in amyloid precursor protein/presenilin1 (APPPS1) transgenic mice on spatial memory, hippocampal long term potentiation (LTP), amyloid pathology, neuroinflammation and…
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Zitierempfehlung
M Hermes, M.P Kummer, T Hammerschmidt, D Terwel, H.C Pape, M.T Heneka (2008) iNOS gene deficiency modifies beta-amyloid deposition, cognitive performance and hippocampal long term potentiation in APPPS1 tg mice. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086926
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