CareLit · DOI-Nachweis · Aktuelle Neurologie
GSK-3beta activation mediates Abeta induced tau pathology in multiple transgenic mice
DOI 10.1055/s-0028-1086929
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Terwel, M.T Heneka
ZeitschriftAktuelle Neurologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Alzheimer's disease (AD) is a complex disorder neuropathologically characterized by extra- and/or intracellular aggregation of toxic Abeta peptide and tau protein species, neuroinflammation, neuronal and synaptic loss. Toxic Abeta species are considered to be upstream in the etiopathological mechanism. We could mimic all neuropathological characteristics except for the tau pathology in mutant V717I amyloid precursor…
Zitieren
Zitierempfehlung
D Terwel, M.T Heneka (2008) GSK-3beta activation mediates Abeta induced tau pathology in multiple transgenic mice. Aktuelle Neurologie (09). https://doi.org/10.1055/s-0028-1086929
Mit CareLit weiterarbeiten