CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
Gene expression of topoisomerase II alpha by microarray analysis is highly prognostic in estrogen receptor (ER)+ breast cancer – prognostic value of Topoisomerase II alpha
DOI 10.1055/s-0028-1088698
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Rody, T Karn, E Ruckhaeberle, V Mueller, R Gaetje, U Holtrich, M Kaufmann
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction Overexpression of Topoisomerase II alpha (TOP2A) has been implicated with gene amplification of the 17q21 amplicon and consecutively with ErbB2 overexpression/ amplification. However, gene amplification is not necessarily a prerequisite for gene expression per se. Methods Large scale analysis was performed using Affymetrix microarray data from n=1681 breast cancer patients to evaluate TOP2A expression.…
Zitieren
Zitierempfehlung
A Rody, T Karn, E Ruckhaeberle, V Mueller, R Gaetje, U Holtrich, M Kaufmann (2008) Gene expression of topoisomerase II alpha by microarray analysis is highly prognostic in estrogen receptor (ER)+ breast cancer – prognostic value of Topoisomerase II alpha. Geburtshilfe und Frauenheilkunde (09). https://doi.org/10.1055/s-0028-1088698
Mit CareLit weiterarbeiten