CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
Expression of metalloprotease insulin-degrading enzyme (insulysin) in breast and ovarian cancer tissues
DOI 10.1055/s-0028-1088826
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Yfanti, K Mengele, G Weirich, C Giersig, M Rosner, M Schmitt
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background. Insulin-degrading enzyme (IDE, insulysin, insulinase; EC 3.4.22.11), a thiol metalloendopeptidase, is involved in intracellular degradation of insulin, thereby inhibiting its translocation and accumulation to the nucleus. Recently, protein expression of IDE has been demonstrated for the first time in the epithelial ducts of normal breast and in breast cancer tissue (Radulescu et al., Int J Oncol 30: 73;…
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Zitierempfehlung
C Yfanti, K Mengele, G Weirich, C Giersig, M Rosner, M Schmitt (2008) Expression of metalloprotease insulin-degrading enzyme (insulysin) in breast and ovarian cancer tissues. Geburtshilfe und Frauenheilkunde (09). https://doi.org/10.1055/s-0028-1088826
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