CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
Down-regulation of a DNA damage barrier in aging human mammary epithelial cells
DOI 10.1055/s-0028-1089144
Bibliografische Angaben
Nachweis in CareLit
Autor:innenT Dörk, B Wieland, B Wieland, M Thren, P Hillemanns, R Hass
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We aimed to investigate the capability of human mammary epithelial cells (HMEC) to respond to ionising radiation with the activation of the ATM-Chk2-p53 DNA damage response. HMEC at different passages were exposed to 0.1–6 Gy of ionising radiation, and cellular radiation responses were assessed by flow cytometry and by immunoblot analyses. Early passages of HMEC phosphorylated p53(Ser15), Nbn(Ser343) and Chk2(Thr68)…
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Zitierempfehlung
T Dörk, B Wieland, B Wieland, M Thren, P Hillemanns, R Hass (2008) Down-regulation of a DNA damage barrier in aging human mammary epithelial cells. Geburtshilfe und Frauenheilkunde (09). https://doi.org/10.1055/s-0028-1089144
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