CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Inhibition of Notch signaling attenuates pancreatic cancer progression
DOI 10.1055/s-0028-1089358
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Autor:innenRR Plentz, S Sankaran, BZ Stanger, PK Majumder, N Bardeesy
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Pancreatic ductal adenocarcinoma (PDAC) is the fourth most common cause of cancer death in the United States. Early diagnosis is rare and treatment options are limited. The Notch pathway has recently emerged as a candidate drug target. Notch signaling regulates the proliferation of pancreatic progenitors during embryogenesis and is reactivated in the earliest PDAC precursor lesions known as PanINs. Thi…
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Zitierempfehlung
RR Plentz, S Sankaran, BZ Stanger, PK Majumder, N Bardeesy (2008) Inhibition of Notch signaling attenuates pancreatic cancer progression. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089358
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