CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Interferon-γ-mediated apoptosis in intestinal epithelial cells: Implications for potentially beneficial cytokine balancing
DOI 10.1055/s-0028-1089383
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Autor:innenD Schuhmann, P Godoy, S Haas, C Stump, J Gundt, S Ehnert, MV Singer, S Dooley, U Böcker
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Interferon (IFN)-γ represents one of the key mediators in the pathogenesis of inflammatory bowel diseases. In our hands, IFN-γ shifts the interleukin (IL)-18/IL-18 binding protein (bp) ratio in intestinal epithelial cells (IEC) towards the latter; however, even in the absence of other pro-apoptotic cytokines, cell death occurs. Aim: To determine the mechanisms involved in IFN-γ mediated cell death of IEC. Meth…
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Zitierempfehlung
D Schuhmann, P Godoy, S Haas, C Stump, J Gundt, S Ehnert, MV Singer, S Dooley, U Böcker (2008) Interferon-γ-mediated apoptosis in intestinal epithelial cells: Implications for potentially beneficial cytokine balancing. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089383
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