CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The NOD2 variants rs2066843 and rs2076756 are novel independent Crohn's disease susceptibility gene variants associated with severe penetrating disease phenotype resulting in frequent need for surgery
DOI 10.1055/s-0028-1089401
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Seiderer, J Glas, J Diegelmann, G Pasciuto, C Tillack, S Pfennig, M Jürgens, A Konrad, HP Török, U Schiemann, T Griga, W Klein, JT Epplen, T Mussack, P Lohse, B Göke, T Ochsenkühn, M Folwaczny, B Müller-Myhsok, S Brand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: A number of studies indicates a strong association of the three common NOD2/CARD15 variants p.R702W, p.G908R, and p.Leu1007fsX1008 with Crohn's disease (CD) while the role of other NOD2 variants has not been investigated in detail. We therefore aimed to test the association and phenotypic consequences of two recently identified NOD2 variants (SNPs rs2066843 and rs2076756) in a large German cohor…
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Zitierempfehlung
J Seiderer, J Glas, J Diegelmann, G Pasciuto, C Tillack, S Pfennig, M Jürgens, A Konrad, HP Török, U Schiemann, T Griga, W Klein, JT Epplen, T Mussack, P Lohse, B Göke, T Ochsenkühn, M Folwaczny, B Müller-Myhsok, S Brand (2008) The NOD2 variants rs2066843 and rs2076756 are novel independent Crohn's disease susceptibility gene variants associated with severe penetrating disease phenotype resulting in frequent need for surgery. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089401
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