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The disease susceptibility risk mediated by gene variants in PHOX2B, NCF4, FAM92B, and in the intergenic region on chromosome 10q21.1 differs between North American and European patients with Crohn's disease

J Diegelmann, J Glas, J Seiderer, G Pasciuto, C Tillack, A Konrad, HP Török, S Pfennig, U Schiemann, W Klein, JT Epplen, T Griga, P Lohse, B Göke, T Ochsenkühn, M Folwaczny, B Müller-Myhsok, S Brand · Zeitschrift für Gastroenterologie · Ausgabe 09/2008

DOI 10.1055/s-0028-1089404

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Autor:innenJ Diegelmann, J Glas, J Seiderer, G Pasciuto, C Tillack, A Konrad, HP Török, S Pfennig, U Schiemann, W Klein, JT Epplen, T Griga, P Lohse, B Göke, T Ochsenkühn, M Folwaczny, B Müller-Myhsok, S Brand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background and Aims: Very recently, a North American genome-wide association study identified three novel gene variants in PHOX2B, NCF4, and FAM92B as well as one SNP (rs224136) in the intergenic region on chromosome 10q21.1 to be associated with Crohn's disease (CD) (Nat Genet 2007;39:596–604.). However, their role in European patients with inflammatory bowel disease is unknown. Therefore, we aimed to replicate the…

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J Diegelmann, J Glas, J Seiderer, G Pasciuto, C Tillack, A Konrad, HP Török, S Pfennig, U Schiemann, W Klein, JT Epplen, T Griga, P Lohse, B Göke, T Ochsenkühn, M Folwaczny, B Müller-Myhsok, S Brand (2008) The disease susceptibility risk mediated by gene variants in PHOX2B, NCF4, FAM92B, and in the intergenic region on chromosome 10q21.1 differs between North American and European patients with Crohn's disease. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089404

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