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Increased expression of the novel IL-10 like cytokine IL-26 in RORγt expressing Th17 cells in patients with active Crohn's disease

J Diegelmann, CJ Auernhammer, B Göke, S Brand · Zeitschrift für Gastroenterologie · Ausgabe 09/2008

DOI 10.1055/s-0028-1089416

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Autor:innenJ Diegelmann, CJ Auernhammer, B Göke, S Brand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben

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Background/Aims: Currently, the role of IL-26, a novel IL-10 like cytokine without murine homologue, in human gastrointestinal disease is completely unknown. The aim of this study was to analyze this novel cytokine system including its expression and transcriptional regulation in intestinal inflammation. Methods: Expression studies were performed by quantitative PCR, Western Blot and immunohistochemistry. IL-26 seru…

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J Diegelmann, CJ Auernhammer, B Göke, S Brand (2008) Increased expression of the novel IL-10 like cytokine IL-26 in RORγt expressing Th17 cells in patients with active Crohn's disease. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089416

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