CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Stress-induced activation of TGF-β and activin A signaling in hepatocytes leads to early expression of connective tissue growth factor (CTGF/CCN2)
DOI 10.1055/s-0028-1089425
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Nachweis in CareLit
Autor:innenAM Gressner, B Lahme, M Siluschek, K Rehbein, OA Gressner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: CTGF, a member of the CCN-family of functionally pluripotent cysteine-rich proteins is a downstream modulator of TGF-β action. Its expression in hepatocytes (PC), recently shown by us, is stimulated by exogenous TGF-β, but up-regulated also spontaneously in complete TGF-β-free culture conditions (1). Aim of this study was to identify potential autocrine mechanisms for CTGF regulation in PC. Methods: In…
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Zitierempfehlung
AM Gressner, B Lahme, M Siluschek, K Rehbein, OA Gressner (2008) Stress-induced activation of TGF-β and activin A signaling in hepatocytes leads to early expression of connective tissue growth factor (CTGF/CCN2). Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089425
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