CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Entecavir at Five Years Shows Long-Term Maintenance of High Genetic Barrier to Hepatitis B Virus Resistance
DOI 10.1055/s-0028-1089435
Bibliografische Angaben
Nachweis in CareLit
Autor:innenDJ Tenney, KA Pokornowski, RE Rose, CJ Baldick, BJ Eggers, J Fang, JY Yang, D Xu, H Brett-Smith, N Spiegelmacher, A Schwendel, T Pichl, I Reeb, RJ Colonno
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Entecavir (ETV) provides both potent viral suppression and a high genetic barrier to resistance, requiring ≥3 resistance substitutions. As a result, in nucleoside-naïve patients, ETV resistance (ETVr) was rare through 4 years. The genetic barrier in lamivudine(LVD)-refractory patients was reduced. Methods: All patients receiving continuous therapy in phase II/III trials were monitored for resistance through ye…
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Zitierempfehlung
DJ Tenney, KA Pokornowski, RE Rose, CJ Baldick, BJ Eggers, J Fang, JY Yang, D Xu, H Brett-Smith, N Spiegelmacher, A Schwendel, T Pichl, I Reeb, RJ Colonno (2008) Entecavir at Five Years Shows Long-Term Maintenance of High Genetic Barrier to Hepatitis B Virus Resistance. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089435
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