CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Association of the c.3972C>T variant of the multidrug resistance-associated protein 2 gene (MRP2/ABCC2) with susceptibility to bile duct cancer
DOI 10.1055/s-0028-1089485
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Autor:innenA Höblinger, F Grünhage, T Sauerbruch, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Multidrug resistance protein 2 (MRP2/ABCC2) is one of the ATP-binding cassette transporters expressed on the apical membrane of hepatocytes and cholangiocytes. ABCC2 plays an important role in the biliary clearance of a wide variety of endogenous and exogenous toxic compounds. In a recent study, the c.3972 C>T (I1324I) variant in exon 28 was significantly associated with hepatocellular carcinoma risk (Meyer-He…
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Zitierempfehlung
A Höblinger, F Grünhage, T Sauerbruch, F Lammert (2008) Association of the c.3972C>T variant of the multidrug resistance-associated protein 2 gene (MRP2/ABCC2) with susceptibility to bile duct cancer. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089485
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