CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
A Cre-loxP based mouse model for conditional somatic gene expression and knock-down in vivo using avian retroviral vectors
DOI 10.1055/s-0028-1089500
Bibliografische Angaben
Nachweis in CareLit
Autor:innenB Seidler, A Schmidt, U Mayr, H Nakkhei, RM Schmid, G Schneider, D Saur
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Site and time-specific somatic gene transfer using the avian sarcoma-leucosis retrovirus RCAS, has been shown to be a powerful tool to analyze gene function in vivo. RCAS retroviruses transduce only mammalian cells genetically engineered to express the avian retroviral receptor, TVA. Here, we have generated a knock-in mouse line termed LSL-R26Tva-lacZ with concomitant conditional expression of TVA and lacZ by target…
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Zitierempfehlung
B Seidler, A Schmidt, U Mayr, H Nakkhei, RM Schmid, G Schneider, D Saur (2008) A Cre-loxP based mouse model for conditional somatic gene expression and knock-down in vivo using avian retroviral vectors. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089500
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