CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Genetic inhibition of telomerase induces alternative lengthening of telomeres (ALT) in genetically defined human esophageal epithelial cells
DOI 10.1055/s-0028-1089514
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Nachweis in CareLit
Autor:innenA Queisser, M Thaler, A von Werder, EM Egenter, S Heeg, N Hirt, H Kunert, S Hauss, H Harada, H Nakagawa, S Li, EH Blackburn, HE Blum, OG Opitz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Immortalization is an important step in malignant transformation of human cells depending on telomere maintenance. This is either mediated through activation of the enzyme telomerase containing a template RNA (hTER) and the core protein (hTERT) or through a recombination based alternative mechanism (ALT). Little is known about the regulation of these two mechanisms in a single cell. We investigated, wh…
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Zitierempfehlung
A Queisser, M Thaler, A von Werder, EM Egenter, S Heeg, N Hirt, H Kunert, S Hauss, H Harada, H Nakagawa, S Li, EH Blackburn, HE Blum, OG Opitz (2008) Genetic inhibition of telomerase induces alternative lengthening of telomeres (ALT) in genetically defined human esophageal epithelial cells. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089514
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