CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Bortezomib is ineffective in an orthotopic mouse model of pancreatic adenocarcinoma
DOI 10.1055/s-0028-1089519
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Nachweis in CareLit
Autor:innenA Märten, S Serba, M von Lilienfeld-Toal, J Schmidt
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The purpose of the present study was to evaluate the potency of the proteasome inhibitor bortezomib±gemcitabine in vitro and in vivo in pancreatic carcinoma. For in vivo testing, an orthotopic syngeneic mouse model which is very close to the biological situation has been used. In particular, the study focused on the impact of bortezomib on angiogenesis. It could be shown that bortezomib induced apoptosis and inhibit…
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Zitierempfehlung
A Märten, S Serba, M von Lilienfeld-Toal, J Schmidt (2008) Bortezomib is ineffective in an orthotopic mouse model of pancreatic adenocarcinoma. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089519
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