CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Characterization of hepatocyte-specific Caspase-8 knockout mice in experimental models of acute liver injury
DOI 10.1055/s-0028-1089613
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Autor:innenC Liedtke, J Freimuth, KL Streetz, N Beraza, D Lambertz, N Gassler, D Riethmacher, C Trautwein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background and Aims: Induction of apoptosis in the liver is related to liver injury eventually resulting in liver failure. Caspase-8 is the most upstream-located protease (caspase) involved in apoptosis mediated by Fas, TNF and related death receptors of the TNF superfamily. The aim of this study was to characterize conditional caspase-8 knockout (KO) mice in different models of experimental liver injury. Methods: C…
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Zitierempfehlung
C Liedtke, J Freimuth, KL Streetz, N Beraza, D Lambertz, N Gassler, D Riethmacher, C Trautwein (2008) Characterization of hepatocyte-specific Caspase-8 knockout mice in experimental models of acute liver injury. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089613
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