CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The etiology of liver damage imparts TGF-beta and/or IL-13 as driving force of fibrogenesis
DOI 10.1055/s-0028-1089617
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Nachweis in CareLit
Autor:innenHL Weng
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
It is discussed if profibrogenic TGF-beta signal transduction is a common feature of any chronic liver disease. Besides TGF-beta, IL-13 increases type I pro-collagen expression in cultured hepatic stellate cells. We determined Smad2 C-terminal serine phosphorylation as indicator for TGF-beta signaling by immunohistochemistry in 237 liver tissues from patients with chronic liver disease based on HBV, HCV and Schistos…
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Zitierempfehlung
HL Weng (2008) The etiology of liver damage imparts TGF-beta and/or IL-13 as driving force of fibrogenesis. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089617
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