CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Telomerase-dependent conditionally replicating adenovirus (hTERT-Ad) expressing carex-PTDs displays enhanced oncolytic properties in nonpermissive tumors
DOI 10.1055/s-0028-1089667
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Ohnhäuser, N Woller, E Gürlevik, MP Manns, S Kubicka, F Kühnel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Conditionally-replicating adenoviruses (CRAds) are challenging tools for therapy of solid tumors. However, adenoviruses do not efficiently spread within many tumors due to the downregulation of the coxsackievirus-adenovirus-receptor (CAR). Our aim was to establish telomerase-dependent conditionally replicating adenoviruses that express bispecific adapter proteins comprising the adenovirus-binding ectodomain of CAR f…
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Zitierempfehlung
K Ohnhäuser, N Woller, E Gürlevik, MP Manns, S Kubicka, F Kühnel (2008) Telomerase-dependent conditionally replicating adenovirus (hTERT-Ad) expressing carex-PTDs displays enhanced oncolytic properties in nonpermissive tumors. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089667
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