CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Expression analysis of the growth factor receptors and ligands EGFR, VEGF-C, VEGF-D and VEGFR3, demonstrates that VEGF-D expression correlates with human colorectal cancer aggressiveness and is downregulated by cetuximab
DOI 10.1055/s-0028-1089668
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Moehler, C Frings, A Mueller, I Gockel, CC Schimanski, S Biesterfeld, P Galle, M Holtmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Purpose: Inappropriate growth factor-dependent signaling contributes to neoplasia. The current analysis explored the impact of high-level expression of the growth factor receptors EGFR and VEGFR3 and the VEGFR3 ligands VEGF-C and VEGF-D on disease progression and prognosis in human colorectal cancer. Furthermore, as the use of EGFR-targeted agents represents a clinically-validated therapeutic approach for the treatm…
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Zitierempfehlung
M Moehler, C Frings, A Mueller, I Gockel, CC Schimanski, S Biesterfeld, P Galle, M Holtmann (2008) Expression analysis of the growth factor receptors and ligands EGFR, VEGF-C, VEGF-D and VEGFR3, demonstrates that VEGF-D expression correlates with human colorectal cancer aggressiveness and is downregulated by cetuximab. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089668
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