CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The oncolytic adenovirus Adp53-sensor for selective replication in p53-altered tumors and potential target spectrum is not limited by the p73 status
DOI 10.1055/s-0028-1089669
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Nachweis in CareLit
Autor:innenF Kühnel, E Gürlevik, T Wirth, L Zender, MP Manns, S Kubicka
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Oncolytic virotherapy provides a promising mean for the treatment of solid tumors. Central goals of virotherapy are tight restriction of viral replication to tumor cells and a broad range of potential target tumors. Aim of our study was the establishment of a conditionally replicating adenovirus able to recognize the transcriptional p53-status of target cells and to consequently respond by the selective onset of vir…
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Zitierempfehlung
F Kühnel, E Gürlevik, T Wirth, L Zender, MP Manns, S Kubicka (2008) The oncolytic adenovirus Adp53-sensor for selective replication in p53-altered tumors and potential target spectrum is not limited by the p73 status. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089669
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