CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The adenoviral vector adsensor-p53t provides a highly selective tool for oncolytic virotherapy of tumors with activated telomerase and aberrations in p53-transcriptional activity
DOI 10.1055/s-0028-1089673
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Autor:innenE Gürlevik, P Schache, N Strüver, MP Manns, F Kühnel, S Kubicka
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Oncolytic virotherapy is a promising and novel mean for treatment of solid tumors. A major challenge in virotherapy is tight restriction of viral replication to malignant cells combined with a large spectrum of potential target tumors. Aim of this study was the generation of a conditionally replicating adenovirus able to both recognize and to respond to activated telomerase and an aberrant transcriptional p53-status…
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Zitierempfehlung
E Gürlevik, P Schache, N Strüver, MP Manns, F Kühnel, S Kubicka (2008) The adenoviral vector adsensor-p53t provides a highly selective tool for oncolytic virotherapy of tumors with activated telomerase and aberrations in p53-transcriptional activity. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0028-1089673
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