CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepatocyte specific NEMO deletion promotes NK/NKT cell dependent liver damage
DOI 10.1055/s-0029-1191752
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Autor:innenN Beraza, Y Malato, LE Sander, M Al-Masaoudi, J Freimuth, D Riethmacher, T Roskams, C Liedtke, C Trautwein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
The nuclear factor kappa B (NF-κB) is essential in the regulation of apoptosis, inflammation, chronic liver disease and progression of cancer. NF-κB is activated after phosphorylation of IκB by the IKK complex. The IKK complex consists in two catalytic subunits IKKa/1 and IKKb/2 and a regulatory subunit IKKγ/NEMO. We generated hepatocyte specific NEMO deleted mice (NEMOΔhepa) that exhibit chronic inflammation, steat…
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Zitierempfehlung
N Beraza, Y Malato, LE Sander, M Al-Masaoudi, J Freimuth, D Riethmacher, T Roskams, C Liedtke, C Trautwein (2009) Hepatocyte specific NEMO deletion promotes NK/NKT cell dependent liver damage. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191752
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