CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Characterization of the TGF-β/Smad signalling pathways and their negative feedback regulators Ski and SnoN in hepatocytes
DOI 10.1055/s-0029-1191760
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Autor:innenL Ciuclan, CS Stump, K Breitkopf, A Müller, MV Singer, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: TGF-β is a profibrotic cytokine that plays a central role in the onset and progression of chronic liver diseases. TGF-β activity is tightly controlled by multiple mechanisms, in which antagonising Smads activities by different co-repressors is an important regulatory component. Aims: In this study, we focus on identifying the role of Ski and SnoN as negative regulators of signal transduction by TGF-β i…
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Zitierempfehlung
L Ciuclan, CS Stump, K Breitkopf, A Müller, MV Singer, S Dooley (2009) Characterization of the TGF-β/Smad signalling pathways and their negative feedback regulators Ski and SnoN in hepatocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191760
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