CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TGF-β enhances alcohol dependent hepatocyte damage via downregulation of alcohol dehydrogenase I
DOI 10.1055/s-0029-1191761
Bibliografische Angaben
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Autor:innenL Ciuclan, C Stump, I Ilkavets, H Weng, MV Singer, K Breitkopf, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The adverse effect of alcohol in liver is mediated via interactions involving oxidative/non-oxidative metabolism, fat deposition and fibrogenic cytokines. This study assessed cross-talk between ethanol and TGF-β signaling in hepatocytes and its contribution to liver damage. To obtain a comprehensive view on TGF-β effects in hepatocytes, an Affymetrix microarray analysis was performed. Results were confirmed by qRT-P…
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Zitierempfehlung
L Ciuclan, C Stump, I Ilkavets, H Weng, MV Singer, K Breitkopf, S Dooley (2009) TGF-β enhances alcohol dependent hepatocyte damage via downregulation of alcohol dehydrogenase I. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191761
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