CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Elevated concentrations of 15-deoxy-Δ12,14-Prostaglandin J2 in chronic liver disease propose therapeutic trials with PPARgamma inducing drugs
DOI 10.1055/s-0029-1191767
Bibliografische Angaben
Nachweis in CareLit
Autor:innenOA Gressner, C Gao, K Rehbein, B Lahme, T Müller, T Berg, AM Gressner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Current knowledge attributes connective tissue growth factor (CTGF/CCN2) a crucial role in hepatic fibrogenesis and–very likely–carcinogenesis. Hepatocytes are the major cellular source of CTGF in the liver in which CTGF is sensitively upregulated by TGF-β. In another abstract, we demonstrate that the methylxanthine derivate caffeine leads to an upregulation of PPARγ expression in hepatocytes, thus sensitizing…
Zitieren
Zitierempfehlung
OA Gressner, C Gao, K Rehbein, B Lahme, T Müller, T Berg, AM Gressner (2009) Elevated concentrations of 15-deoxy-Δ12,14-Prostaglandin J2 in chronic liver disease propose therapeutic trials with PPARgamma inducing drugs. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191767
Mit CareLit weiterarbeiten