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Expression of smooth muscle cell markers in activated hepatic stellate cells is connected to MAP kinase regulated transcription levels of serum response factor (SRF)

J Herrmann, U Haas, AM Gressner, R Weiskirchen · Zeitschrift für Gastroenterologie · Ausgabe 01/2009

DOI 10.1055/s-0029-1191775

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Autor:innenJ Herrmann, U Haas, AM Gressner, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Activation of hepatic stellate cells (HSC) is a major event in liver fibrogenesis. A typical feature of activated HSC is the expression of α-smooth muscle actin (SMA) and other smooth muscle cell (SMC) marker genes. The transcription of these genes is mainly regulated by the transcription factor ‘serum response factor’ (SRF) [1]. Less is known about transcriptional control of the SRF gene itself. We could recently d…

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J Herrmann, U Haas, AM Gressner, R Weiskirchen (2009) Expression of smooth muscle cell markers in activated hepatic stellate cells is connected to MAP kinase regulated transcription levels of serum response factor (SRF). Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191775

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