CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Deletion of the platelet derived chemokine PF4 (CXCL4) limits liver fibrosis in vivo
DOI 10.1055/s-0029-1191790
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Autor:innenM Moreno Zaldivar, K Pauels, M Berres, P Schmitz, N Gassler, C Weber, R Weiskirchen, C Trautwein, HE Wasmuth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Chemokines are inflammatory mediators during acute and chronic liver injury. The chemokine PF4 (CXCL4) is the only chemokine which is mainly secreted by platelets. PF4 has been shown to interact with RANTES (CCL5), thereby increasing monocyte arrest to endothelium. As RANTES has been shown to stimulate hepatic stellate cells and platelets are thought to contribute to liver fibrosis, PF4 might be an interesting…
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Zitierempfehlung
M Moreno Zaldivar, K Pauels, M Berres, P Schmitz, N Gassler, C Weber, R Weiskirchen, C Trautwein, HE Wasmuth (2009) Deletion of the platelet derived chemokine PF4 (CXCL4) limits liver fibrosis in vivo. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191790
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