CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TGF-β induces IL-15 in hepatocytes. Is it then opposing TGFβ in a negative feedback manner? Does this mechanism play a role in liver disease?
DOI 10.1055/s-0029-1191792
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Munker, P Godoy, E Bulanova, H Weng, A Bachmann, S Bulfone-Paus, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Liver fibrogenesis is a process involving the participation of several cellular components. We described a new role for hepatocytes in the process of fibrogenesis, in which TGFbeta induces expression and secretion of CTGF, another potent profibrogenic cytokine. Recently Interleukin-15 has emerged as a new player in several models of liver damage, but its precise role has not yet been determined. Real Time PCR showed…
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Zitierempfehlung
S Munker, P Godoy, E Bulanova, H Weng, A Bachmann, S Bulfone-Paus, S Dooley (2009) TGF-β induces IL-15 in hepatocytes. Is it then opposing TGFβ in a negative feedback manner? Does this mechanism play a role in liver disease?. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191792
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