CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Bid-mediated apoptosis does not contribute to cholestatic liver injury following bile duct ligation
DOI 10.1055/s-0029-1191793
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Autor:innenP Nalapareddy, S Schüngel, MP Manns, H Jaeschke, A Vogel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Death receptor-mediated hepatocyte apoptosis has been implicated in bile acid induced apoptosis of hepatocytes in vitro and in vivo. The BH3-interacting domain death agonist Bid is a critical mediator for apoptosis induced by activation of Fas and TNF-R1 death receptors in hepatocytes. Multiple studies have shown that bile acids induce Fas-dependent hepatocyte apoptosis in vitro providing a cellular mechanism for bi…
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Zitierempfehlung
P Nalapareddy, S Schüngel, MP Manns, H Jaeschke, A Vogel (2009) Bid-mediated apoptosis does not contribute to cholestatic liver injury following bile duct ligation. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191793
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