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Toll-like receptor activated hepatic stellate cells are potent regulators of hepatitis C virus replication

B Wang · Zeitschrift für Gastroenterologie · Ausgabe 01/2009

DOI 10.1055/s-0029-1191807

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Autor:innenB Wang
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben

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Aims: While hepatic stellate cells (HSC) are known to be key mediators of liver fibrosis, only little is known about their role in the innate immune system of the liver., Methods: To address this question, murine HSCs were isolated from livers of C57BL/6J mice and human HSCs were isolated from liver samples obtained from resections. HSC were stimulated with TLR1–9 ligands for 20h. Expression of TNF-α, IFN-α, IFN-β a…

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B Wang (2009) Toll-like receptor activated hepatic stellate cells are potent regulators of hepatitis C virus replication. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191807

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