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Coordinate regulation of the human UDP-glucuronosyltransferase 1A10 gene by aryl hydrocarbon receptor (AhR) and nuclear factor erythroid 2-related factor 2 (Nrf2)

S Kalthoff, U Ehmer, N Freiberg, MP Manns, CP Strassburg · Zeitschrift für Gastroenterologie · Ausgabe 01/2009

DOI 10.1055/s-0029-1191831

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Autor:innenS Kalthoff, U Ehmer, N Freiberg, MP Manns, CP Strassburg
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: UDP-glucuronosyltransferases (UGTs) catalyze an important metabolic process in which many xenobiotics and endobiotics are converted to water soluble compounds facilitating elimination from the body. UGT1A10 is capable of glucuronidating a number of phenolic compounds, steroids and benzo[a]pyrene, which are associated with carcinogenesis and inflammation. Aim of this study was the characterization of tr…

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S Kalthoff, U Ehmer, N Freiberg, MP Manns, CP Strassburg (2009) Coordinate regulation of the human UDP-glucuronosyltransferase 1A10 gene by aryl hydrocarbon receptor (AhR) and nuclear factor erythroid 2-related factor 2 (Nrf2). Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191831

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