CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Regulation of nuclear receptors in non-alcoholic fatty liver disease: insights from ob/ob-mice
DOI 10.1055/s-0029-1191836
Bibliografische Angaben
Nachweis in CareLit
Autor:innenIV Martin, A Minkenberg, S Strauch, A Geier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Non-alcoholic fatty liver diseases (NAFLD) affects ≤25% of the general population. Several nuclear receptors (NR) have been implied in the progression of NAFLD, e.g. through the regulation of FAS by Lrh-1, LXR and FXR and induction of PPARγ which is activated by PXR and influences Srebp-1c expression. KO-mice-studies assigned FXR a protective role in fatty liver development whereas the absence of SHP a…
Zitieren
Zitierempfehlung
IV Martin, A Minkenberg, S Strauch, A Geier (2009) Regulation of nuclear receptors in non-alcoholic fatty liver disease: insights from ob/ob-mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191836
Mit CareLit weiterarbeiten