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Chemotherapy-induced apoptosis in hepatocellular carcinoma (HCC) involves activation of the p53 family and is mediated by signaling via death receptors and mitochondria

SJ Seitz, AE Schulze Schleithoff, AF Koch, K Lorenz, W Stremmel, M Müller · Zeitschrift für Gastroenterologie · Ausgabe 01/2009

DOI 10.1055/s-0029-1191902

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Autor:innenSJ Seitz, AE Schulze Schleithoff, AF Koch, K Lorenz, W Stremmel, M Müller
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

In HCC patients, conventional chemo- and radiation therapy fail. This failure is mainly due to resistance towards apoptosis. Therefore, current attempts to improve the survival of HCC patients will have to include strategies that specifically target tumor cell resistance towards apoptosis. However, the molecular determinants, which confer resistance of HCC cells towards chemotherapeutic agents, have not yet been ful…

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SJ Seitz, AE Schulze Schleithoff, AF Koch, K Lorenz, W Stremmel, M Müller (2009) Chemotherapy-induced apoptosis in hepatocellular carcinoma (HCC) involves activation of the p53 family and is mediated by signaling via death receptors and mitochondria. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191902

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