CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepatic Endotoxin Receptor CD14 Expression in Chronic Hepatitis C Patients with regard to rs2569190/C159T Genetic Variants
DOI 10.1055/s-0029-1191924
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Autor:innenR Bregadze, J Mertens, E Askar, A Mansur, G Ramadori, S Mihm
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Objective: The single nucleotide polymorphism rs2569190 within the CD14 endotoxin (LPS) receptor gene was found to be associated with liver fibrosis progression in patients with alcoholic liver disease. Because of this association and further in vitro experiments the T allele is suggested to sensitize the liver for endogenous, gut-derived LPS via an enhanced hepatic CD14 expression. Materials and Methods: To investi…
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Zitierempfehlung
R Bregadze, J Mertens, E Askar, A Mansur, G Ramadori, S Mihm (2009) Hepatic Endotoxin Receptor CD14 Expression in Chronic Hepatitis C Patients with regard to rs2569190/C159T Genetic Variants. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191924
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