CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The hepatitis C virus non-structural 3/4A protease activates Akt-dependent host cell signaling which is required for sufficient viral replication
DOI 10.1055/s-0029-1191925
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Autor:innenED Brenndörfer, J Karthe, P Cebula, A Erhardt, L Frelin, J Schulte am Esch, D Häussinger, JG Bode, M Sällberg
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
The hepatitis C virus (HCV) interferes with several cellular signaling pathways to warrant viral replication as well as survival of the infected cell and to protect the infected cell from antiviral efector mechanisms of the host. Thus it counteracts the interferon response to viral infection through non-structural 3/4A (NS3/4A) protease-mediated cleavage of CARDIF and TRIF thereby interrupting an important part of t…
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Zitierempfehlung
ED Brenndörfer, J Karthe, P Cebula, A Erhardt, L Frelin, J Schulte am Esch, D Häussinger, JG Bode, M Sällberg (2009) The hepatitis C virus non-structural 3/4A protease activates Akt-dependent host cell signaling which is required for sufficient viral replication. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191925
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