CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The interferon stimulated gene 15 functions as a proviral factor for HCV and is enhanced in the liver of patients with genotype 1
DOI 10.1055/s-0029-1191926
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Autor:innenR Bröring, M Trippler, G Gerken, JF Schlaak
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: The outcome of HCV standard combination therapy has previously been associated with a strong hepatic up-regulation of a subset of interferon stimulated genes (ISGs), one of them is ISG15. The aim of this study was to further elucidate the functional role of ISG15 in HCV infection. Methods: ISG15 gene expression was suppressed in human (con1) and murine (MH1) hepatoma cells harbouring the HCV con1 replicon I377…
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Zitierempfehlung
R Bröring, M Trippler, G Gerken, JF Schlaak (2009) The interferon stimulated gene 15 functions as a proviral factor for HCV and is enhanced in the liver of patients with genotype 1. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191926
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